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Hepatitis C Virus Non-Structural Protein 5A (NS5A) Disrupts Mitochondrial Dynamics and Induces Mitophagy

Mitophagy is a selective form of autophagy, targeting damaged mitochondria for lysosomal degradation. Although HCV infection has been shown to induce mitophagy, the precise underlying mechanism and the effector protein responsible remain unclear. Herein, we demonstrated that the HCV non-structural p...

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Detalles Bibliográficos
Autores principales: Jassey, Alagie, Liu, Ching-Hsuan, Changou, Chun A., Richardson, Christopher D., Hsu, Hsue-Yin, Lin, Liang-Tzung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523690/
https://www.ncbi.nlm.nih.gov/pubmed/30934919
http://dx.doi.org/10.3390/cells8040290