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Hepatitis C Virus Non-Structural Protein 5A (NS5A) Disrupts Mitochondrial Dynamics and Induces Mitophagy
Mitophagy is a selective form of autophagy, targeting damaged mitochondria for lysosomal degradation. Although HCV infection has been shown to induce mitophagy, the precise underlying mechanism and the effector protein responsible remain unclear. Herein, we demonstrated that the HCV non-structural p...
Autores principales: | Jassey, Alagie, Liu, Ching-Hsuan, Changou, Chun A., Richardson, Christopher D., Hsu, Hsue-Yin, Lin, Liang-Tzung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523690/ https://www.ncbi.nlm.nih.gov/pubmed/30934919 http://dx.doi.org/10.3390/cells8040290 |
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