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HILIC-Enabled (13)C Metabolomics Strategies: Comparing Quantitative Precision and Spectral Accuracy of QTOF High- and QQQ Low-Resolution Mass Spectrometry

Dynamic (13)C-tracer-based flux analyses of in vivo reaction networks still require a continuous development of advanced quantification methods applying state-of-the-art mass spectrometry platforms. Utilizing alkaline HILIC chromatography, we adapt strategies for a systematic quantification study in...

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Detalles Bibliográficos
Autores principales: Feith, André, Teleki, Attila, Graf, Michaela, Favilli, Lorenzo, Takors, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523712/
https://www.ncbi.nlm.nih.gov/pubmed/30986989
http://dx.doi.org/10.3390/metabo9040063