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The PTEN–PI3K Axis in Cancer

The PI3K–AKT–mTOR signal transduction pathway regulates a variety of biological processes including cell growth, cell cycle progression and proliferation, cellular metabolism, and cytoskeleton reorganization. Fine-tuning of the phosphatidylinositol 3-kinase (PI3K) pathway signaling output is essenti...

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Detalles Bibliográficos
Autores principales: Papa, Antonella, Pandolfi, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523724/
https://www.ncbi.nlm.nih.gov/pubmed/30999672
http://dx.doi.org/10.3390/biom9040153