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A Low-Molecular-Weight Polyethylenimine/pDNA-VEGF Polyplex System Constructed in a One-Pot Manner for Hindlimb Ischemia Therapy

Peripheral arterial disease (PAD) is often characterized by continued reduction in blood flow supply to limbs. Advanced therapeutic strategies like gene therapy could potentially be applied to limb ischemia therapy. However, developing a gene delivery system with low toxicity and high efficiency rem...

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Detalles Bibliográficos
Autores principales: Guo, Xiaoshuang, Yuan, Zihan, Xu, Yang, Zhao, Xiaotian, Fang, Zhiwei, Yuan, Wei-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523750/
https://www.ncbi.nlm.nih.gov/pubmed/30965617
http://dx.doi.org/10.3390/pharmaceutics11040171