CD44 Promotes Migration and Invasion of Docetaxel-Resistant Prostate Cancer Cells Likely via Induction of Hippo-Yap Signaling

Patients receiving docetaxel developed a drug resistance within a few months. We generated docetaxel-resistant PC/DX25 and DU/DX50 CRPC cells from PC-3 and DU-145 PCa cells, respectively. We investigated the mechanism behind why PC/DX25 and DU/DX50 cells exhibited higher migration and invasion abili...

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Detalles Bibliográficos
Autores principales: Lai, Chih-Jen, Lin, Ching-Yu, Liao, Wen-Ying, Hour, Tzyh-Chyuan, Wang, Horng-Dar, Chuu, Chih-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523775/
https://www.ncbi.nlm.nih.gov/pubmed/30935014
http://dx.doi.org/10.3390/cells8040295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523775/
https://www.ncbi.nlm.nih.gov/pubmed/30935014
http://dx.doi.org/10.3390/cells8040295

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