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CD44 Promotes Migration and Invasion of Docetaxel-Resistant Prostate Cancer Cells Likely via Induction of Hippo-Yap Signaling

Patients receiving docetaxel developed a drug resistance within a few months. We generated docetaxel-resistant PC/DX25 and DU/DX50 CRPC cells from PC-3 and DU-145 PCa cells, respectively. We investigated the mechanism behind why PC/DX25 and DU/DX50 cells exhibited higher migration and invasion abili...

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Detalles Bibliográficos
Autores principales:	Lai, Chih-Jen, Lin, Ching-Yu, Liao, Wen-Ying, Hour, Tzyh-Chyuan, Wang, Horng-Dar, Chuu, Chih-Pin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523775/ https://www.ncbi.nlm.nih.gov/pubmed/30935014 http://dx.doi.org/10.3390/cells8040295

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