Functional Characterization of Clinically-Relevant Rare Variants in ABCG2 Identified in a Gout and Hyperuricemia Cohort

ATP-binding cassette subfamily G member 2 (ABCG2) is a physiologically important urate transporter. Accumulating evidence demonstrates that congenital dysfunction of ABCG2 is an important genetic risk factor in gout and hyperuricemia; recent studies suggest the clinical significance of both common a...

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Detalles Bibliográficos
Autores principales: Toyoda, Yu, Mančíková, Andrea, Krylov, Vladimír, Morimoto, Keito, Pavelcová, Kateřina, Bohatá, Jana, Pavelka, Karel, Pavlíková, Markéta, Suzuki, Hiroshi, Matsuo, Hirotaka, Takada, Tappei, Stiburkova, Blanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523779/
https://www.ncbi.nlm.nih.gov/pubmed/31003562
http://dx.doi.org/10.3390/cells8040363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523779/
https://www.ncbi.nlm.nih.gov/pubmed/31003562
http://dx.doi.org/10.3390/cells8040363

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