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Regulating the BCL2 Family to Improve Sensitivity to Microtubule Targeting Agents
Chemotherapeutic targeting of microtubules has been the standard of care in treating a variety of malignancies for decades. During mitosis, increased microtubule dynamics are necessary for mitotic spindle formation and successful chromosomal segregation. Microtubule targeting agents (MTAs) disrupt t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523793/ https://www.ncbi.nlm.nih.gov/pubmed/31013740 http://dx.doi.org/10.3390/cells8040346 |