Cargando…

Regulating the BCL2 Family to Improve Sensitivity to Microtubule Targeting Agents

Chemotherapeutic targeting of microtubules has been the standard of care in treating a variety of malignancies for decades. During mitosis, increased microtubule dynamics are necessary for mitotic spindle formation and successful chromosomal segregation. Microtubule targeting agents (MTAs) disrupt t...

Descripción completa

Detalles Bibliográficos
Autores principales: Whitaker, Robert H., Placzek, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523793/
https://www.ncbi.nlm.nih.gov/pubmed/31013740
http://dx.doi.org/10.3390/cells8040346