Cargando…
Regulating the BCL2 Family to Improve Sensitivity to Microtubule Targeting Agents
Chemotherapeutic targeting of microtubules has been the standard of care in treating a variety of malignancies for decades. During mitosis, increased microtubule dynamics are necessary for mitotic spindle formation and successful chromosomal segregation. Microtubule targeting agents (MTAs) disrupt t...
Autores principales: | Whitaker, Robert H., Placzek, William J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523793/ https://www.ncbi.nlm.nih.gov/pubmed/31013740 http://dx.doi.org/10.3390/cells8040346 |
Ejemplares similares
-
Post-Transcriptional Regulation of Anti-Apoptotic BCL2 Family Members
por: Cui, Jia, et al.
Publicado: (2018) -
Glioma Stem Cells Are Sensitized to BCL-2 Family Inhibition by Compromising Histone Deacetylases
por: Merati, Aran, et al.
Publicado: (2023) -
Novel microtubule-targeting agents – the epothilones
por: Cheng, Kit L, et al.
Publicado: (2008) -
Bcl-B: an “unknown” protein of the Bcl-2 family
por: Pervushin, N. V., et al.
Publicado: (2023) -
Targeting BCL-2 regulated apoptosis in cancer
por: Campbell, Kirsteen J., et al.
Publicado: (2018)