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Mutagenesis of DsbAss is Crucial for the Signal Recognition Particle Mechanism in Escherichia coli: Insights from Molecular Dynamics Simulations

The disulfide bond signal sequence (DsbAss) protein is characterized as an important virulence factor in gram-negative bacteria. This study aimed to analyze the “alanine” alteration in the hydrophobic (H) region of DsbAss and to understand the conformational DsbAss alteration(s) inside the fifty-fou...

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Detalles Bibliográficos
Autores principales: Durrani, Faiza Gul, Gul, Roquyya, Mirza, Muhammad Usman, Kaderbhai, Naheed Nazly, Froeyen, Matheus, Saleem, Mahjabeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523802/
https://www.ncbi.nlm.nih.gov/pubmed/30987187
http://dx.doi.org/10.3390/biom9040133