Cargando…

Mutagenesis of DsbAss is Crucial for the Signal Recognition Particle Mechanism in Escherichia coli: Insights from Molecular Dynamics Simulations

The disulfide bond signal sequence (DsbAss) protein is characterized as an important virulence factor in gram-negative bacteria. This study aimed to analyze the “alanine” alteration in the hydrophobic (H) region of DsbAss and to understand the conformational DsbAss alteration(s) inside the fifty-fou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Durrani, Faiza Gul, Gul, Roquyya, Mirza, Muhammad Usman, Kaderbhai, Naheed Nazly, Froeyen, Matheus, Saleem, Mahjabeen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523802/ https://www.ncbi.nlm.nih.gov/pubmed/30987187 http://dx.doi.org/10.3390/biom9040133

Ejemplares similares

A Putative Prophylactic Solution for COVID-19: Development of Novel Multiepitope Vaccine Candidate against SARS-COV-2 by Comprehensive Immunoinformatic and Molecular Modelling Approach
por: Rehman, Hafiz Muzzammel, et al.
Publicado: (2020)

Molecular Characterization, Structural Modeling, and Evaluation of Antimicrobial Activity of Basrai Thaumatin-Like Protein against Fungal Infection
por: Yasmin, Nusrat, et al.
Publicado: (2017)

Metabolic Fingerprint Analysis of Cytochrome b(5)-producing E. coli N4830-1 Using FT-IR Spectroscopy
por: Tengsuttiwat, Thanyaporn, et al.
Publicado: (2022)

Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase
por: Mirza, Muhammad Usman, et al.
Publicado: (2020)

Protein disulfide bond generation in Escherichia coli DsbB–DsbA
por: Inaba, Kenji
Publicado: (2008)

A Computational Approach to Modeling an Antagonistic Angiogenic VEGFR1-IL2 Fusion Protein for Cancer Therapy
por: Shafique, Qurrat ul Ain, et al.
Publicado: (2021)

Soluble Production, Characterization, and Structural Aesthetics of an Industrially Important Thermostable β-Glucosidase from Clostridium thermocellum in Escherichia coli
por: Ahmed, Syed Shoaib, et al.
Publicado: (2019)

Identification of novel human USP2 inhibitor and its putative role in treatment of COVID-19 by inhibiting SARS-CoV-2 papain-like (PLpro) protease
por: Mirza, Muhammad Usman, et al.
Publicado: (2020)

The Learned Ass
Publicado: (1896)

Entropy-Driven Mechanisms between Disulfide-Bond Formation Protein A (DsbA) and B (DsbB) in Escherichia coli
por: Yazawa, Kenjiro, et al.
Publicado: (2019)

Identification of NS2B-NS3 Protease Inhibitors for Therapeutic Application in ZIKV Infection: A Pharmacophore-Based High-Throughput Virtual Screening and MD Simulations Approaches
por: Rehman, Hafiz Muzzammel, et al.
Publicado: (2023)

Identification of RdRp inhibitors against SARS-CoV-2 through E-pharmacophore-based virtual screening, molecular docking and MD simulations approaches
por: Rehman, Hafiz Muzzammel, et al.
Publicado: (2023)

And Baalam’s Ass Spake
Publicado: (1901)

The golden ass : being the metamorphoses of Lucius Apuleius
Publicado: (1915)

The golden ass : being the metamorphoses of Lucius Apuleius
por: Lucius Apuleius
Publicado: (1965)

Each actor on his ass
por: Mac Liammóir, Micheál, 1899-1978
Publicado: (1961)

A Leadership Kick in the Ass
por: Treasurer, Bill
Publicado: (2017)

Feeding Infants with Asses’ Milk
Publicado: (1889)

Attempt to Infect the Ass with Tuberculin
Publicado: (1899)

In silico structural elucidation of RNA-dependent RNA polymerase towards the identification of potential Crimean-Congo Hemorrhagic Fever Virus inhibitors
por: Mirza, Muhammad Usman, et al.
Publicado: (2019)

Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens
por: Totsika, Makrina, et al.
Publicado: (2018)

Toxicity Evaluation of the Naphthalen-2-yl 3,5-Dinitrobenzoate: A Drug Candidate for Alzheimer Disease
por: Anwar, Fareeha, et al.
Publicado: (2021)

American Ass’n of Obstetricians and Gynecologists
Publicado: (1909)

Stone in the Bladder of a She-ass
por: Schimmel, W. C.
Publicado: (1896)

Transactions of the Amer. Med. Ass., for 1850
Publicado: (1851)

Transactions of Amer. Med. Ass’n.
Publicado: (1871)

Trans. Am. Med. Ass. 1856
Publicado: (1857)

A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA
por: Wang, Geqing, et al.
Publicado: (2023)

Quantification of Berberine in Berberis vulgaris L. Root Extract and Its Curative and Prophylactic Role in Cisplatin-Induced In Vivo Toxicity and In Vitro Cytotoxicity
por: Ahmad, Sarfraz, et al.
Publicado: (2019)

Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila
por: De Mena, Lorena, et al.
Publicado: (2020)

Long-term persistence of crAss-like phage crAss001 is associated with phase variation in Bacteroides intestinalis
por: Shkoporov, Andrey N., et al.
Publicado: (2021)

Functional Genomics Via Metabolic Footprinting: Monitoring Metabolite Secretion by Escherichia Coli Tryptophan Metabolism Mutants Using FT–IR and Direct Injection Electrospray Mass Spectrometry
por: Kaderbhai, Naheed N., et al.
Publicado: (2003)

Deleterious Variants in WNT10A, EDAR, and EDA Causing Isolated and Syndromic Tooth Agenesis: A Structural Perspective from Molecular Dynamics Simulations
por: Parveen, Asia, et al.
Publicado: (2019)

Physicians’ Mutual Benefit Ass’n of Texas
Publicado: (1887)

Programme: Texas State Medical Ass’n
Publicado: (1887)

Address before the Rocky Mountain Med. Ass.
Publicado: (1878)

Relationship among DNA double‐strand break (DSB), DSB repair, and transcription prevents genome instability and cancer
por: Ui, Ayako, et al.
Publicado: (2020)

Heterologous Secretory Expression and Characterization of Dimerized Bone Morphogenetic Protein 2 in Bacillus subtilis
por: Hanif, Muhammad Umair, et al.
Publicado: (2017)

Effect of Berberis vulgaris L. root extract on ifosfamide-induced in vivo toxicity and in vitro cytotoxicity
por: Ilyas, Shazia, et al.
Publicado: (2021)

Isolation and characterisation of ΦcrAss002, a crAss-like phage from the human gut that infects Bacteroides xylanisolvens
por: Guerin, Emma, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p9qkdf6reli6p5i95dp96ekefi