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YAP, ΔNp63, and β-Catenin Signaling Pathways Are Involved in the Modulation of Corneal Epithelial Stem Cell Phenotype Induced by Substrate Stiffness

Recent studies have established that the phenotype of epithelial stem cells residing in the corneal periphery (the limbus) depends on this niche’s distinct biomechanical properties. However, the signaling pathways underlying this dependency are still poorly understood. To address this issue, we inve...

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Detalles Bibliográficos
Autores principales: Gouveia, Ricardo M., Vajda, Flora, Wibowo, Jason A., Figueiredo, Francisco, Connon, Che J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523807/
https://www.ncbi.nlm.nih.gov/pubmed/31013745
http://dx.doi.org/10.3390/cells8040347