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Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments

Renal fibrosis is the common pathway for most forms of progressive renal disease. The Unilateral Ureteral Obstruction (UUO) model is used to cause renal fibrosis, where the primary feature of UUO is tubular injury as a result of obstructed urine flow. Furthermore, experimental UUO in rodents is beli...

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Detalles Bibliográficos
Autores principales: Martínez-Klimova, Elena, Aparicio-Trejo, Omar Emiliano, Tapia, Edilia, Pedraza-Chaverri, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523883/
https://www.ncbi.nlm.nih.gov/pubmed/30965656
http://dx.doi.org/10.3390/biom9040141