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Computational Methods for Detection of Differentially Methylated Regions Using Kernel Distance and Scan Statistics

Motivation: Researchers in genomics are increasingly interested in epigenetic factors such as DNA methylation because they play an important role in regulating gene expression without changes in the sequence of DNA. Abnormal DNA methylation is associated with many human diseases. Results: We propose...

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Detalles Bibliográficos
Autores principales: Dunbar, Faith, Xu, Hongyan, Ryu, Duchwan, Ghosh, Santu, Shi, Huidong, George, Varghese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523914/
https://www.ncbi.nlm.nih.gov/pubmed/31013791
http://dx.doi.org/10.3390/genes10040298