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Development of a Transdermal Delivery System for Tenofovir Alafenamide, a Prodrug of Tenofovir with Potent Antiviral Activity Against HIV and HBV

Tenofovir alafenamide (TAF) is an effective nucleotide reverse transcriptase inhibitor that is used in the treatment of HIV-1 and HBV. Currently, it is being investigated for HIV prophylaxis. Oral TAF regimens require daily intake, which hampers adherence and increases the possibility of viral resis...

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Detalles Bibliográficos
Autores principales: Puri, Ashana, Bhattaccharjee, Sonalika A., Zhang, Wei, Clark, Meredith, Singh, Onkar N., Doncel, Gustavo F., Banga, Ajay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523937/
https://www.ncbi.nlm.nih.gov/pubmed/30970630
http://dx.doi.org/10.3390/pharmaceutics11040173