Synthesis of an Undecasaccharide Featuring an Oligomannosidic Heptasaccharide and a Bacterial Kdo-lipid A Backbone for Eliciting Neutralizing Antibodies to Mammalian Oligomannose on the HIV-1 Envelope Spike

[Image: see text] Lipooligosaccharides (LOS) from the bacterium Rhizobium radiobacter Rv3 are structurally related to antigenic mammalian oligomannoses on the HIV-1 envelope glycoprotein spike that are targets for broadly neutralizing antibodies. Here, we prepared a hybrid structure of viral and bac...

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Detalles Bibliográficos
Autores principales: Trattnig, Nino, Blaukopf, Markus, Bruxelle, Jean-François, Pantophlet, Ralph, Kosma, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524000/
https://www.ncbi.nlm.nih.gov/pubmed/31010286
http://dx.doi.org/10.1021/jacs.9b02872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524000/
https://www.ncbi.nlm.nih.gov/pubmed/31010286
http://dx.doi.org/10.1021/jacs.9b02872

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