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Synthesis of an Undecasaccharide Featuring an Oligomannosidic Heptasaccharide and a Bacterial Kdo-lipid A Backbone for Eliciting Neutralizing Antibodies to Mammalian Oligomannose on the HIV-1 Envelope Spike

[Image: see text] Lipooligosaccharides (LOS) from the bacterium Rhizobium radiobacter Rv3 are structurally related to antigenic mammalian oligomannoses on the HIV-1 envelope glycoprotein spike that are targets for broadly neutralizing antibodies. Here, we prepared a hybrid structure of viral and bac...

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Detalles Bibliográficos
Autores principales:	Trattnig, Nino, Blaukopf, Markus, Bruxelle, Jean-François, Pantophlet, Ralph, Kosma, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524000/ https://www.ncbi.nlm.nih.gov/pubmed/31010286 http://dx.doi.org/10.1021/jacs.9b02872

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