5-Arylidene(chromenyl-methylene)-thiazolidinediones: Potential New Agents against Mutant Oncoproteins K-Ras, N-Ras and B-Raf in Colorectal Cancer and Melanoma

Background and objectives: Cancer represents the miscommunication between and within the body cells. The mutations of the oncogenes encoding the MAPK pathways play an important role in the development of tumoral diseases. The mutations of KRAS and BRAF oncogenes are involved in colorectal cancer and...

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Detalles Bibliográficos
Autores principales: Nastasă, Cristina, Tamaian, Radu, Oniga, Ovidiu, Tiperciuc, Brîndușa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524019/
https://www.ncbi.nlm.nih.gov/pubmed/30935124
http://dx.doi.org/10.3390/medicina55040085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524019/
https://www.ncbi.nlm.nih.gov/pubmed/30935124
http://dx.doi.org/10.3390/medicina55040085

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