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In vitro evaluation of complement deposition and opsonophagocytic killing of Rhodococcus equi mediated by poly‐N‐acetyl glucosamine hyperimmune plasma compared to commercial plasma products

BACKGROUND: The bacterium Rhodococcus equi can cause severe pneumonia in foals. The absence of a licensed vaccine and limited effectiveness of commercial R. equi hyperimmune plasma (RE‐HIP) create a great need for improved prevention of this disease. HYPOTHESIS: Plasma hyperimmune to the capsular po...

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Detalles Bibliográficos
Autores principales: Folmar, Chelsea N., Cywes‐Bentley, Colette, Bordin, Angela I., Rocha, Joana N., Bray, Jocelyne M., Kahn, Susanne K., Schuckert, Amanda E., Pier, Gerald B., Cohen, Noah D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524092/
https://www.ncbi.nlm.nih.gov/pubmed/31034109
http://dx.doi.org/10.1111/jvim.15511