Cargando…

Circulating Cell-Free mtDNA Contributes to AIM2 Inflammasome-Mediated Chronic Inflammation in Patients with Type 2 Diabetes

Mitochondrial dysfunction has been implicated in the pathogenesis of insulin resistance and type 2 diabetes. Damaged mitochondria DNA (mtDNA) may have a role in regulating hyperglycemia during type 2 diabetes. Circulating cell-free mitochondria DNA (ccf-mtDNA) was found in serum and plasma from pati...

Descripción completa

Detalles Bibliográficos
Autores principales: Bae, Jung Hwan, Jo, Seung, Kim, Seong Jin, Lee, Jong Min, Jeong, Ji Hun, Kang, Jeong Suk, Cho, Nam-Jun, Kim, Sang Soo, Lee, Eun Young, Moon, Jong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524162/
https://www.ncbi.nlm.nih.gov/pubmed/30965677
http://dx.doi.org/10.3390/cells8040328