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FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury

Idiopathic pulmonary fibrosis is a common form of interstitial lung disease resulting in alveolar remodeling and progressive loss of pulmonary function because of chronic alveolar injury and failure to regenerate the respiratory epithelium. Histologically, fibrotic lesions and honeycomb structures e...

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Detalles Bibliográficos
Autores principales: Yuan, Tingting, Volckaert, Thomas, Redente, Elizabeth F., Hopkins, Seantel, Klinkhammer, Kylie, Wasnick, Roxana, Chao, Cho-Ming, Yuan, Jie, Zhang, Jin-San, Yao, Changfu, Majka, Susan, Stripp, Barry R., Günther, Andreas, Riches, David W.H., Bellusci, Saverio, Thannickal, Victor J., De Langhe, Stijn P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524168/
https://www.ncbi.nlm.nih.gov/pubmed/31056475
http://dx.doi.org/10.1016/j.stemcr.2019.04.003