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Dehydrocostus lactone inhibits in vitro gastrinoma cancer cell growth through apoptosis induction, sub-G1 cell cycle arrest, DNA damage and loss of mitochondrial membrane potential

INTRODUCTION: The purpose of the present study was to evaluate the antiproliferative activity of dehydrocostus lactone against human BON-1 cancer cell lines and to explore the possible underlying mechanism. MATERIAL AND METHODS: MTT cell viability assay was used to determine cytotoxic effects of deh...

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Detalles Bibliográficos
Autores principales: Long, Hou-yong, Huang, Qing-xian, Yu, Yong-yang, Zhang, Zhen-bin, Yao, Zeng-wu, Chen, Hong-bing, Feng, Jun-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524172/
https://www.ncbi.nlm.nih.gov/pubmed/31110544
http://dx.doi.org/10.5114/aoms.2018.73128