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The ubiquitin ligase CHIP modulates cellular behaviors of gastric cancer cells by regulating TRAF2

BACKGROUND: CHIP is an E3 ubiquitin ligase that plays contrast roles in diverse human malignancies, depending on its targets. To date, the mechanisms underlying the function of CHIP in gastric cancer remains unclear. Here, we aim to further clarify the effects of CHIP on the development and progress...

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Detalles Bibliográficos
Autores principales: Dai, Hanjue, Chen, Hao, Xu, Jingjing, Zhou, Jun, Shan, Zhili, Yang, Hengying, Zhou, Xiaojun, Guo, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524225/
https://www.ncbi.nlm.nih.gov/pubmed/31130821
http://dx.doi.org/10.1186/s12935-019-0832-z