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NeoMutate: an ensemble machine learning framework for the prediction of somatic mutations in cancer
BACKGROUND: The accurate screening of tumor genomic landscapes for somatic mutations using high-throughput sequencing involves a crucial step in precise clinical diagnosis and targeted therapy. However, the complex inherent features of cancer tissue, especially, tumor genetic intra-heterogeneity cou...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524241/ https://www.ncbi.nlm.nih.gov/pubmed/31096972 http://dx.doi.org/10.1186/s12920-019-0508-5 |