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Influence of a Hyperglycemic Microenvironment on a Diabetic Versus Healthy Rat Vascular Endothelium Reveals Distinguishable Mechanistic and Phenotypic Responses

Hyperglycemia is a critical factor in the development of endothelial dysfunction in type 2 diabetes mellitus (T2DM). Whether hyperglycemic states result in a disruption of similar molecular mechanisms in endothelial cells under both diabetic and non-diabetic states, remains largely unknown. This stu...

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Detalles Bibliográficos
Autores principales: Haspula, Dhanush, Vallejos, Andrew K., Moore, Timothy M., Tomar, Namrata, Dash, Ranjan K., Hoffmann, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524400/
https://www.ncbi.nlm.nih.gov/pubmed/31133884
http://dx.doi.org/10.3389/fphys.2019.00558