Involvement of insulin receptor substrates in cognitive impairment and Alzheimer’s disease

Type 2 diabetes—associated with impaired insulin/insulin-like growth factor-1 (IGF1) signaling (IIS)—is a risk factor for cognitive impairment and dementia including Alzheimer’s disease (AD). The insulin receptor substrate (IRS) proteins are major components of IIS, which transmit upstream signals v...

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Detalles Bibliográficos
Autores principales: Tanokashira, Daisuke, Fukuokaya, Wataru, Taguchi, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524492/
https://www.ncbi.nlm.nih.gov/pubmed/30964050
http://dx.doi.org/10.4103/1673-5374.253535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524492/
https://www.ncbi.nlm.nih.gov/pubmed/30964050
http://dx.doi.org/10.4103/1673-5374.253535

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