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Meningeal Mast Cells Contribute to ATP-Induced Nociceptive Firing in Trigeminal Nerve Terminals: Direct and Indirect Purinergic Mechanisms Triggering Migraine Pain

Peripheral mechanisms of primary headaches such as a migraine remain unclear. Meningeal afferents surrounded by multiple mast cells have been suggested as a major source of migraine pain. Extracellular ATP released during migraine attacks is a likely candidate for activating meningeal afferents via...

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Detalles Bibliográficos
Autores principales: Koroleva, Ksenia, Gafurov, Oleg, Guselnikova, Valeriia, Nurkhametova, Dilyara, Giniatullina, Raisa, Sitdikova, Guzel, Mattila, Olli S., Lindsberg, Perttu J., Malm, Tarja Maarit, Giniatullin, Rashid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524559/
https://www.ncbi.nlm.nih.gov/pubmed/31133812
http://dx.doi.org/10.3389/fncel.2019.00195