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Tissue Transglutaminase Appears in Monocytes and Macrophages but Not in Lymphocytes in White Matter Multiple Sclerosis Lesions

Leukocyte infiltration is an important pathological hallmark of multiple sclerosis (MS) and is therefore targeted by current MS therapies. The enzyme tissue transglutaminase (TG2) contributes to monocyte/macrophage migration and is present in MS lesions and could be a potential therapeutic target. W...

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Detalles Bibliográficos
Autores principales: Chrobok, Navina L, Bol, John G J M, Wilhelmus, Micha M M, Drukarch, Benjamin, van Dam, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524631/
https://www.ncbi.nlm.nih.gov/pubmed/31058279
http://dx.doi.org/10.1093/jnen/nlz030