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Hematopoietic or Osteoclast-Specific Deletion of Syk Leads to Increased Bone Mass in Experimental Mice

Syk is a non-receptor tyrosine kinase critically involved in signaling by various immunoreceptors including B-cell-receptors and activating Fc-receptors. We have previously shown that Syk also mediates immunoreceptor-like signals required for the in vitro development and function of osteoclasts. How...

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Detalles Bibliográficos
Autores principales: Csete, Dániel, Simon, Edina, Alatshan, Ahmad, Aradi, Petra, Dobó-Nagy, Csaba, Jakus, Zoltán, Benkő, Szilvia, Győri, Dávid S., Mócsai, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524727/
https://www.ncbi.nlm.nih.gov/pubmed/31134061
http://dx.doi.org/10.3389/fimmu.2019.00937