Cargando…

Quantitative Mechanistic Modeling in Support of Pharmacological Therapeutics Development in Immuno-Oncology

Following the approval, in recent years, of the first immune checkpoint inhibitor, there has been an explosion in the development of immuno-modulating pharmacological modalities for the treatment of various cancers. From the discovery phase to late-stage clinical testing and regulatory approval, cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Peskov, Kirill, Azarov, Ivan, Chu, Lulu, Voronova, Veronika, Kosinsky, Yuri, Helmlinger, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524731/
https://www.ncbi.nlm.nih.gov/pubmed/31134058
http://dx.doi.org/10.3389/fimmu.2019.00924