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Quantitative Mechanistic Modeling in Support of Pharmacological Therapeutics Development in Immuno-Oncology
Following the approval, in recent years, of the first immune checkpoint inhibitor, there has been an explosion in the development of immuno-modulating pharmacological modalities for the treatment of various cancers. From the discovery phase to late-stage clinical testing and regulatory approval, cha...
Autores principales: | Peskov, Kirill, Azarov, Ivan, Chu, Lulu, Voronova, Veronika, Kosinsky, Yuri, Helmlinger, Gabriel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524731/ https://www.ncbi.nlm.nih.gov/pubmed/31134058 http://dx.doi.org/10.3389/fimmu.2019.00924 |
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