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Context-Dependent Impact of RAS Oncogene Expression on Cellular Reprogramming to Pluripotency
Induction of pluripotency in somatic cells with defined genetic factors has been successfully used to investigate the mechanisms of disease initiation and progression. Cellular reprogramming and oncogenic transformation share common features; both involve undergoing a dramatic change in cell identit...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524732/ https://www.ncbi.nlm.nih.gov/pubmed/31056476 http://dx.doi.org/10.1016/j.stemcr.2019.04.006 |