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WNT/NOTCH Pathway Is Essential for the Maintenance and Expansion of Human MGE Progenitors

Medial ganglionic eminence (MGE)-like cells yielded from human pluripotent stem cells (hPSCs) hold great potentials for cell therapies of related neurological disorders. However, cues that orchestrate the maintenance versus differentiation of human MGE progenitors, and ways for large-scale expansion...

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Detalles Bibliográficos
Autores principales: Ma, Lin, Wang, Yiran, Hui, Yi, Du, Yanhua, Chen, Zhenyu, Feng, Hexi, Zhang, Shuwei, Li, Nan, Song, Jianren, Fang, Yujiang, Xu, Xiangjie, Shi, Lei, Zhang, Bowen, Cheng, Jiayi, Zhou, Shanshan, Liu, Ling, Zhang, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524734/
https://www.ncbi.nlm.nih.gov/pubmed/31056478
http://dx.doi.org/10.1016/j.stemcr.2019.04.007