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Using equivalence class counts for fast and accurate testing of differential transcript usage

Background: RNA sequencing has enabled high-throughput and fine-grained quantitative analyses of the transcriptome. While differential gene expression is the most widely used application of this technology, RNA-seq data also has the resolution to infer differential transcript usage (DTU), which can...

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Detalles Bibliográficos
Autores principales: Cmero, Marek, Davidson, Nadia M., Oshlack, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524746/
https://www.ncbi.nlm.nih.gov/pubmed/31143443
http://dx.doi.org/10.12688/f1000research.18276.2