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Pluripotent Stem Cell-Derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins

The process of oligodendrogenesis has been relatively well delineated in the rodent brain. However, it remains unknown whether analogous developmental processes are manifested in the human brain. Here we report oligodendrogenesis in forebrain organoids, generated by using OLIG2-GFP knockin human plu...

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Detalles Bibliográficos
Autores principales: Kim, Hyosung, Xu, Ranjie, Padmashri, Ragunathan, Dunaevsky, Anna, Liu, Ying, Dreyfus, Cheryl F., Jiang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524754/
https://www.ncbi.nlm.nih.gov/pubmed/31091434
http://dx.doi.org/10.1016/j.stemcr.2019.04.011