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In-utero epigenetic factors are associated with early-onset myopia in young children

OBJECTIVES: To assess whether epigenetic mechanisms affecting gene expression may be involved in the pathogenesis of early-onset myopia, we performed genome-wide DNA methylation analyses of umbilical cord tissues, and assessed any associations between CpG site-specific methylation and the developmen...

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Detalles Bibliográficos
Autores principales: Seow, Wei Jie, Ngo, Cheryl S., Pan, Hong, Barathi, Veluchamy Amutha, Tompson, Stuart W., Whisenhunt, Kristina N., Vithana, Eranga, Chong, Yap-Seng, Juo, Suh-Hang H., Hysi, Pirro, Young, Terri L., Karnani, Neerja, Saw, Seang Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524791/
https://www.ncbi.nlm.nih.gov/pubmed/31100065
http://dx.doi.org/10.1371/journal.pone.0214791