Impact of selective immune-cell depletion on growth of Mycobacterium tuberculosis (Mtb) in a whole-blood bactericidal activity (WBA) assay

We investigated the contribution of host immune cells to bacterial killing in a whole-blood bactericidal activity (WBA) assay, an ex vivo model used to test efficacy of drugs against mycobacterium tuberculosis (Mtb). We performed WBA assays with immuno-magnetic depletion of specific cell types, in t...

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Detalles Bibliográficos
Autores principales: Cross, Gail B., Yeo, Benjamin C-M, Hutchinson, Paul Edward, Tan, Mark C., Verma, Rupangi, Lu, Qingshu, Paton, Nicholas I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524797/
https://www.ncbi.nlm.nih.gov/pubmed/31100071
http://dx.doi.org/10.1371/journal.pone.0216616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524797/
https://www.ncbi.nlm.nih.gov/pubmed/31100071
http://dx.doi.org/10.1371/journal.pone.0216616

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