Cargando…

Impact of selective immune-cell depletion on growth of Mycobacterium tuberculosis (Mtb) in a whole-blood bactericidal activity (WBA) assay

We investigated the contribution of host immune cells to bacterial killing in a whole-blood bactericidal activity (WBA) assay, an ex vivo model used to test efficacy of drugs against mycobacterium tuberculosis (Mtb). We performed WBA assays with immuno-magnetic depletion of specific cell types, in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cross, Gail B., Yeo, Benjamin C-M, Hutchinson, Paul Edward, Tan, Mark C., Verma, Rupangi, Lu, Qingshu, Paton, Nicholas I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524797/ https://www.ncbi.nlm.nih.gov/pubmed/31100071 http://dx.doi.org/10.1371/journal.pone.0216616

Ejemplares similares

Adjunctive use of celecoxib with anti-tuberculosis drugs: evaluation in a whole-blood bactericidal activity model
por: Naftalin, Claire M., et al.
Publicado: (2018)

Pyrogen detection methods: Comparison of bovine whole blood assay (bWBA) and monocyte activation test (MAT)
por: Wunderlich, Christian, et al.
Publicado: (2014)

Evaluation of the Xpert® MTB/RIF assay and microscopy for the diagnosis of Mycobacterium tuberculosis in Namibia
por: Mavenyengwa, Rooyen T., et al.
Publicado: (2017)

Mycobactericidal Activity of Sutezolid (PNU-100480) in Sputum (EBA) and Blood (WBA) of Patients with Pulmonary Tuberculosis
por: Wallis, Robert S., et al.
Publicado: (2014)

Detection of Mycobacterium tuberculosis in AFB smear-negative sputum specimens through MTB culture and GeneXpert(®) MTB/RIF assay
por: Rasool, Ghulam, et al.
Publicado: (2019)

Utility of the REBA MTB-rifa® assay for rapid detection of rifampicin resistant Mycobacterium Tuberculosis
por: Cho, Eunjin, et al.
Publicado: (2013)

Revised Device Labeling for the Cepheid Xpert MTB/RIF Assay for Detecting Mycobacterium tuberculosis
Publicado: (2015)

GeneXpert(®) MTB/RIF assay with transbronchial lung cryobiopsy for Mycobacterium tuberculosis diagnosis
por: Sánchez-Cabral, Olivia, et al.
Publicado: (2020)

Evaluation of Xpert MTB/RIF assay for detection of Mycobacterium tuberculosis in stool samples of adults with pulmonary tuberculosis
por: Rahman, S. M. Mazidur, et al.
Publicado: (2018)

MTB-PCDB: Mycobacterium tuberculosis proteome comparison database
por: Jena, Lingaraja, et al.
Publicado: (2011)

Xpert MTB/RIF Assay Shows Faster Clearance of Mycobacterium tuberculosis DNA with Higher Levels of Rifapentine Exposure
por: Jayakumar, A., et al.
Publicado: (2016)

8‐Hydroxyquinolines are bactericidal against Mycobacterium tuberculosis
por: Odingo, Joshua O., et al.
Publicado: (2019)

Comparison of Xpert MTB/RIF Assay and the Conventional Sputum Microscopy in Detecting Mycobacterium tuberculosis in Northern Thailand
por: Pinyopornpanish, Kanokwan, et al.
Publicado: (2015)

Detection of Mycobacterium tuberculosis (MTB) in Fecal Specimens From Adults Diagnosed With Pulmonary Tuberculosis Using the Xpert MTB/Rifampicin Test
por: Kokuto, Hiroyuki, et al.
Publicado: (2015)

Impact of Larger Sputum Volume on Xpert(®) MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis
por: Badal-Faesen, Sharlaa, et al.
Publicado: (2017)

Mycobacterium tuberculosis thymidylate kinase antigen assays for designating incipient, high-risk latent M.tb infection
por: Wayengera, Misaki, et al.
Publicado: (2018)

EBUS-GS with the GeneXpert MTB/RIF assay for diagnosis of Mycobacterium tuberculosis infection of isolated pulmonary nodules
por: Cao, Jie, et al.
Publicado: (2023)

Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults
por: Kohli, Mikashmi, et al.
Publicado: (2021)

Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children
por: Kay, Alexander W, et al.
Publicado: (2020)

Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults
por: Steingart, Karen R, et al.
Publicado: (2014)

Xpert® Mtb/Rif assay for pulmonary tuberculosis and rifampicin resistance in adults
por: Steingart, Karen R, et al.
Publicado: (2013)

Pulmonary Tuberculosis and Rifampicin Resistant Mycobacterium Tuberculosis in Children and Adolescents using Gene Xpert MTB/RIF Assay in Tigray, Northern Ethiopia
por: Dejene, Tsehaye Asmelash, et al.
Publicado: (2023)

Construction of an Expression Vector Containing Mtb72F of Mycobacterium tuberculosis
por: Nabavinia, Maryam Sadat, et al.
Publicado: (2012)

Xpert(®) MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance
por: Kohli, Mikashmi, et al.
Publicado: (2018)

The Magnitude of MTB and Rifampicin Resistance MTB Using Xpert-MTB/RIF Assay Among Tuberculosis Suspected Patients in Gedeo Zone, Southern Ethiopia
por: Diriba, Kuma, et al.
Publicado: (2021)

Apurinic/Apyrimidinic Endonucleases of Mycobacterium tuberculosis Protect against DNA Damage but Are Dispensable for the Growth of the Pathogen in Guinea Pigs
por: Puri, Rupangi Verma, et al.
Publicado: (2014)

Detection of Mycobacterium tuberculosis and Rifampicin Resistance Using GeneXpert MTB/RIF Assay at Enat Hospital, Central Ethiopia
por: Selfegna, Sebsib, et al.
Publicado: (2022)

Detection of Mycobacterium tuberculosis Complex Using the Xpert MTB/RIF Ultra Assay on the Stool of Pediatric Patients in Dushanbe, Tajikistan
por: Rekart, Michael L., et al.
Publicado: (2023)

Assessment of the Diagnostic Utility of GeneXpert Mycobacterium tuberculosis/Rifampicin (MTB/RIF) Assay in the Suspected Cases of Tuberculous Meningitis
por: Patel, Sakshi, et al.
Publicado: (2023)

Annotated Whole-Genome Shotgun Sequence of Multidrug-Resistant Mycobacterium tuberculosis MTB13_M Isolated from Morocco
por: Lahlou, L., et al.
Publicado: (2017)

Diagnostic Accuracy of the Truenat MTB Plus Assay and Comparison with the Xpert MTB/RIF Assay to Detect Tuberculosis among Hospital Outpatients in Cameroon
por: Ngangue, Yannick Russel, et al.
Publicado: (2022)

Evaluation of Xpert MTB/RIF Assay, MTB Culture and Line Probe Assay for the Detection of MDR Tuberculosis in AFB Smear Negative Specimens
por: Lama, Chandri, et al.
Publicado: (2022)

P285: Comparison of two nucleic acid amplification assays, the probetec et assay and xpert mtb/rif assay, for detection of mycobacterium tuberculosis in respiratory specimens
por: Aljohani, S, et al.
Publicado: (2013)

Utility of the GeneXpert Mycobacterium tuberculosis/Rifampin (MTB/RIF) Assay on Paraffin-Embedded Biopsy Tissue Samples for Detecting Tuberculosis: Comparison With Histopathology
por: Hashmi, Atif A, et al.
Publicado: (2020)

Endonuclease IV Is the Major Apurinic/Apyrimidinic Endonuclease in Mycobacterium tuberculosis and Is Important for Protection against Oxidative Damage
por: Puri, Rupangi Verma, et al.
Publicado: (2013)

Secreted Acid Phosphatase (SapM) of Mycobacterium tuberculosis Is Indispensable for Arresting Phagosomal Maturation and Growth of the Pathogen in Guinea Pig Tissues
por: Puri, Rupangi Verma, et al.
Publicado: (2013)

Utility of Xpert MTB/RIF Assay for Diagnosis of Pediatric Tuberculosis Under Programmatic Conditions in India
por: Yadav, Rakesh, et al.
Publicado: (2020)

Rapid Diagnosis of Mycobacterium tuberculosis with Truenat MTB: A Near-Care Approach
por: Nikam, Chaitali, et al.
Publicado: (2013)

Establishment of an indirect ELISA for Mycobacterium tuberculosis MTB39A protein antibody
por: Wang, Pu, et al.
Publicado: (2023)

Rapid and Accurate Detection of Mycobacterium tuberculosis in Sputum Samples by Cepheid Xpert MTB/RIF Assay—A Clinical Validation Study
por: Rachow, Andrea, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_gqs735paqtepapm8abgspd1cr9