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Effects of Plasmin on von Willebrand Factor and Platelets: A Narrative Review

Plasmin is the major fibrinolytic protease responsible for dissolving thrombi by cleavage of its primary substrate fibrin. In addition, emerging evidence points to other roles of plasmin: (1) as a back-up for ADAMTS13 in proteolysis of ultra-large von Willebrand factor (VWF) multimers and (2) as an...

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Detalles Bibliográficos
Autores principales: van der Vorm, Lisa N., Remijn, Jasper A., de Laat, Bas, Huskens, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524877/
https://www.ncbi.nlm.nih.gov/pubmed/31249945
http://dx.doi.org/10.1055/s-0038-1660505