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TULA-2 Deficiency Enhances Platelet Functional Responses to CLEC-2 Agonists

Platelet activation is essential for hemostasis. Central to platelet activation are the signals transmitted through surface receptors such as glycoprotein VI, the protease-activated receptors, and C-type lectin-like receptor 2 (CLEC-2). CLEC-2 is a HemITAM (hem-immunoreceptor tyrosine activation mot...

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Detalles Bibliográficos
Autores principales: Kostyak, John C., Mauri, Benjamin R., Dangelmaier, Carol, Patel, Akruti, Zhou, Yuhang, Eble, Johannes A., Tsygankov, Alexander Y., McKenzie, Steven E., Kunapuli, Satya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524918/
https://www.ncbi.nlm.nih.gov/pubmed/31249969
http://dx.doi.org/10.1055/s-0038-1676358