Pathological ASXL1 Mutations and Protein Variants Impair Neural Crest Development

The neural crest (NC) gives rise to a multitude of fetal tissues, and its misregulation is implicated in congenital malformations. Here, we investigated molecular mechanisms pertaining to NC-related symptoms in Bohring-Opitz syndrome (BOS), a developmental disorder linked to mutations in the Polycom...

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Detalles Bibliográficos
Autores principales: Matheus, Friederike, Rusha, Ejona, Rehimi, Rizwan, Molitor, Lena, Pertek, Anna, Modic, Miha, Feederle, Regina, Flatley, Andrew, Kremmer, Elisabeth, Geerlof, Arie, Rishko, Valentyna, Rada-Iglesias, Alvaro, Drukker, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524927/
https://www.ncbi.nlm.nih.gov/pubmed/31006630
http://dx.doi.org/10.1016/j.stemcr.2019.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524927/
https://www.ncbi.nlm.nih.gov/pubmed/31006630
http://dx.doi.org/10.1016/j.stemcr.2019.03.006

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