Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans

Reduced protein homeostasis leading to increased protein instability is a common molecular feature of aging, but it remains unclear whether this is a cause or consequence of the aging process. In neurodegenerative diseases and other amyloidoses, specific proteins self-assemble into amyloid fibrils a...

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Detalles Bibliográficos
Autores principales: Huang, Chaolie, Wagner-Valladolid, Sara, Stephens, Amberley D, Jung, Raimund, Poudel, Chetan, Sinnige, Tessa, Lechler, Marie C, Schlörit, Nicole, Lu, Meng, Laine, Romain F, Michel, Claire H, Vendruscolo, Michele, Kaminski, Clemens F, Kaminski Schierle, Gabriele S, David, Della C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524967/
https://www.ncbi.nlm.nih.gov/pubmed/31050339
http://dx.doi.org/10.7554/eLife.43059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524967/
https://www.ncbi.nlm.nih.gov/pubmed/31050339
http://dx.doi.org/10.7554/eLife.43059

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