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Lysostaphin and BMP-2 co-delivery reduces S. aureus infection and regenerates critical-sized segmental bone defects

Staphylococcus aureus is the most common pathogen associated with bacterial infections in orthopedic procedures. Infections often lead to implant failure and subsequent removal, motivating the development of bifunctional materials that both promote repair and prevent failure due to infection. Lysost...

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Detalles Bibliográficos
Autores principales: Johnson, Christopher T., Sok, Mary Caitlin P., Martin, Karen E., Kalelkar, Pranav P., Caplin, Jeremy D., Botchwey, Edward A., García, Andrés J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524983/
https://www.ncbi.nlm.nih.gov/pubmed/31114804
http://dx.doi.org/10.1126/sciadv.aaw1228