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Lysostaphin and BMP-2 co-delivery reduces S. aureus infection and regenerates critical-sized segmental bone defects
Staphylococcus aureus is the most common pathogen associated with bacterial infections in orthopedic procedures. Infections often lead to implant failure and subsequent removal, motivating the development of bifunctional materials that both promote repair and prevent failure due to infection. Lysost...
Autores principales: | Johnson, Christopher T., Sok, Mary Caitlin P., Martin, Karen E., Kalelkar, Pranav P., Caplin, Jeremy D., Botchwey, Edward A., García, Andrés J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524983/ https://www.ncbi.nlm.nih.gov/pubmed/31114804 http://dx.doi.org/10.1126/sciadv.aaw1228 |
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