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Pharmacokinetics of fixed-dose combination of atorvastatin and metformin compared with individual tablets

Purpose: The aims of this study was to investigate the mutual pharmacokinetic interactions between steady-state atorvastatin and metformin and the effect of food on the fixed-dose combined (FDC) tablet of atorvastatin and metformin extended release (XR). Subjects and methods: Study 1, an open-labele...

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Detalles Bibliográficos
Autores principales: Ghim, Jong-Lyul, Phuong, Nguyen Thi Thu, Kim, Min Jung, Kim, Eun-Ji, Song, Geun Seog, Ahn, Sangzin, Shin, Jae-Gook, Kim, Eun-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525001/
https://www.ncbi.nlm.nih.gov/pubmed/31190741
http://dx.doi.org/10.2147/DDDT.S193254