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CNS-Wide over Expression of Fractalkine Improves Cognitive Functioning in a Tauopathy Model

Accumulating evidence increasingly implicates regulation of neuroinflammation as a potential therapeutic target in Alzheimer’s disease and other neurodegenerative disorders. Fractalkine (FKN) is a unique chemokine that is expressed and secreted by neurons and reduces expression of pro-inflammatory g...

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Detalles Bibliográficos
Autores principales: Finneran, Dylan J., Morgan, Dave, Gordon, Marcia N., Nash, Kevin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525127/
https://www.ncbi.nlm.nih.gov/pubmed/30499006
http://dx.doi.org/10.1007/s11481-018-9822-5