Cargando…
CNS-Wide over Expression of Fractalkine Improves Cognitive Functioning in a Tauopathy Model
Accumulating evidence increasingly implicates regulation of neuroinflammation as a potential therapeutic target in Alzheimer’s disease and other neurodegenerative disorders. Fractalkine (FKN) is a unique chemokine that is expressed and secreted by neurons and reduces expression of pro-inflammatory g...
Autores principales: | Finneran, Dylan J., Morgan, Dave, Gordon, Marcia N., Nash, Kevin R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525127/ https://www.ncbi.nlm.nih.gov/pubmed/30499006 http://dx.doi.org/10.1007/s11481-018-9822-5 |
Ejemplares similares
-
Neuroinflammation and fractalkine signaling in Alzheimer’s disease
por: Finneran, Dylan J., et al.
Publicado: (2019) -
CCL2 Overexpression in the Brain Promotes Glial Activation and Accelerates Tau Pathology in a Mouse Model of Tauopathy
por: Joly-Amado, Aurelie, et al.
Publicado: (2020) -
Examination of the Fractalkine and Fractalkine Receptor Expression in Fallopian Adenocarcinoma Reveals Differences When Compared to Ovarian Carcinoma
por: Gurler, Hilal, et al.
Publicado: (2015) -
Ligand-competent fractalkine receptor is expressed on exosomes
por: Park, Eun Jeong, et al.
Publicado: (2021) -
Toward Development of Neuron Specific Transduction After Systemic Delivery of Viral Vectors
por: Finneran, Dylan J., et al.
Publicado: (2021)