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Autologous mesenchymal stem cell implantation, hydroxyapatite, bone morphogenetic protein-2, and internal fixation for treating critical-sized defects: a translational study

INTRODUCTION: Critical-sized defect (CSD) is one of the most challenging cases for orthopaedic surgeons. We aim to explore the therapeutic potential of the combination of bone marrow-derived mesenchymal stem cells (BM-MSCs), hydroxyapatite (HA) granules, bone morphogenetic protein-2 (BMP-2), and int...

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Detalles Bibliográficos
Autores principales: Dilogo, Ismail Hadisoebroto, Phedy, Phedy, Kholinne, Erica, Djaja, Yoshi Pratama, Fiolin, Jessica, Kusnadi, Yuyus, Yulisa, Nyimas Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525135/
https://www.ncbi.nlm.nih.gov/pubmed/30747273
http://dx.doi.org/10.1007/s00264-019-04307-z