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6mA-DNA-binding factor Jumu controls maternal-to-zygotic transition upstream of Zelda

A long-standing question in the field of embryogenesis is how the zygotic genome is precisely activated by maternal factors, allowing normal early embryonic development. We have previously shown that N6-methyladenine (6mA) DNA modification is highly dynamic in early Drosophila embryos and forms an e...

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Detalles Bibliográficos
Autores principales: He, Shunmin, Zhang, Guoqiang, Wang, Jiajia, Gao, Yajie, Sun, Ruidi, Cao, Zhijie, Chen, Zhenping, Zheng, Xiudeng, Yuan, Jiao, Luo, Yuewan, Wang, Xiaona, Zhang, Wenxin, Zhang, Peng, Zhao, Yi, He, Chuan, Tao, Yi, Sun, Qinmiao, Chen, Dahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525185/
https://www.ncbi.nlm.nih.gov/pubmed/31101825
http://dx.doi.org/10.1038/s41467-019-10202-3